Gut commensal Bifidobacterium-derived extracellular vesicles modulate the therapeutic effects of anti-PD-1 in lung cancer

Gut commensal Bifidobacterium-derived extracellular vesicles modulate the therapeutic effects of anti-PD-1 in lung cancer

Abstract Lung cancer is the leading cause of cancer-related deaths worldwide. Although immunotherapy such as anti-programmed death-1 and its ligand 1 (PD-1/L1) is a standard treatment for advanced non-small cell lung cancer (NSCLC), many patients do not derive benefit directly. Several studies have...

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Main Authors: Ranjan Preet, Md Atiqul Islam, Jiyoung Shim, Ganeshkumar Rajendran, Amrita Mitra, Vikalp Vishwakarma, Caleb Kutz, Sonali Choudhury, Harsh Pathak, Qun Dai, Weijing Sun, Rashna Madan, Cuncong Zhong, Mary A. Markiewicz, Jun Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58553-4
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https://doi.org/10.1038/s41467-025-58553-4

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