Oroxylin A may promote cell apoptosis and inhibit epithelial-mesenchymal transition in endometrial cancer, associated with the ERβ/PI3K/AKT pathway

Oroxylin A may promote cell apoptosis and inhibit epithelial-mesenchymal transition in endometrial cancer, associated with the ERβ/PI3K/AKT pathway

Abstract Endometrial cancer (EC) is a prevalent gynecological cancer worldwide, often associated with poor prognosis after recurrence or metastasis. Oroxylin A (OA) is an active flavonoid compound with a strong anti-tumor function. However, the effects of OA on EC remain unknown. In this study, we p...

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Bibliographic Details
Main Authors: Xue Fan, Luming Wu, Tong Cheng, Weilong Lv, Jiao Tian, Jijun Tao, Shiyan Tu, Fangjun Tan, Yiqing Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Oroxylin A
Endometrial cancer
ERβ
Apoptosis
EMT
Online Access:https://doi.org/10.1038/s41598-025-97122-z
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https://doi.org/10.1038/s41598-025-97122-z

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