The role of intrinsically disordered regions of SARS-CoV-2 nucleocapsid and non-structural protein 1 proteins

The role of intrinsically disordered regions of SARS-CoV-2 nucleocapsid and non-structural protein 1 proteins

Virus survival inside the host cell depends on the intricate mechanisms that recruit proteins involved in the arms race. Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) proteome exhibits important levels of structural order. However, some of the SARS-CoV-2 proteins, such as the Nucleoca...

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Bibliographic Details
Main Authors: Getasew Shitaye, Nataliia Ventserova, Gianluca D’Abrosca, Martina Dragone, Eunice Wairimu Maina, Roberto Fattorusso, Rosa Iacovino, Luigi Russo, Carla Isernia, Gaetano Malgieri
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Chemistry
Subjects:
intrinsically disordered proteins
coronaviruses
SARS-COV-2 variants
protein-protein interactions
host-viral interactions
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2025.1597656/full
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https://www.frontiersin.org/articles/10.3389/fchem.2025.1597656/full

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