Structural basis of response regulator inhibition by a bacterial anti-activator protein.

The complex interplay between the response regulator ComA, the anti-activator RapF, and the signaling peptide PhrF controls competence development in Bacillus subtilis. More specifically, ComA drives the expression of genetic competence genes, while RapF inhibits the interaction of ComA with its tar...

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Bibliographic Details
Main Authors: Melinda D Baker, Matthew B Neiditch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1001226&type=printable
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