Analysis of Bacterial Communities and Prediction of Functions and Phenotypes in the Preparation of High Temperature Daqu Using Different Methods

To compare and analyze the similarities and differences in the bacterial community structure of high temperature Daqu prepared by artificial starter-making and mechanical starter-making, this study used Illumina MiSeq high-throughput sequencing technology to analyze the bacterial community compositi...

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Main Authors: Huijun ZHAO, Yurong WANG, Qiangchuan HOU, Haibo ZHANG, Longxin TIAN, Mingbo YE, Zhuang GUO
Format: Article
Language:zho
Published: The editorial department of Science and Technology of Food Industry 2025-04-01
Series:Shipin gongye ke-ji
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Online Access:http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024040452
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author Huijun ZHAO
Yurong WANG
Qiangchuan HOU
Haibo ZHANG
Longxin TIAN
Mingbo YE
Zhuang GUO
author_facet Huijun ZHAO
Yurong WANG
Qiangchuan HOU
Haibo ZHANG
Longxin TIAN
Mingbo YE
Zhuang GUO
author_sort Huijun ZHAO
collection DOAJ
description To compare and analyze the similarities and differences in the bacterial community structure of high temperature Daqu prepared by artificial starter-making and mechanical starter-making, this study used Illumina MiSeq high-throughput sequencing technology to analyze the bacterial community composition of two types of high temperature Daqu samples, and predicted the genetic function and phenotype of the bacteria. Through α-diversity found that there was no significant difference in the diversity and richness of bacteria between artificial and mechanical starter-making samples (P>0.05). The β-diversity showed that there were significant structural differences between the two types of high temperature Daqu samples (P<0.01), and the difference of the bacterial flora of the mechanical starter-making samples was relatively smaller. The analysis of bacterial community structure showed that compared with artificial starter-making samples, the content of Lentibacillus from mechanical starter-making samples was significantly higher (P<0.001), while the content of Weissella, Brevibacterium and Pediococcus was relatively lower (P>0.05). Through LEfSe analysis, it was found that Thermoactinomycetaceae was the biomarker of foot bending, and Bacillaceae was the biomarker of mechanism bending. Through gene function prediction, it was found that compared with artificial starter-making, the signal transduction mechanism of the bacteria in the high-temperature Daqu prepared by mechanical starter-making was significantly higher, and the intracellular transport, secretion and vesicle transport were significantly lower (P<0.05). Through phenotype prediction, it was found that the content of gram-positive bacteria in the mechanical starter-making samples was more abundant (P<0.05), while the ability of oxidative stress tolerance in the artificial starter-making samples was stronger (P<0.05). It could be seen that there were significant differences in the bacterial flora structure between the artificial and mechanical starter-making Daqu, which further affected the function and phenotype of the bacteria. This study can provide basic theory and disciplinary basis for promoting the development of Maotai-flavor Baijiu starter-making samples technology.
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publisher The editorial department of Science and Technology of Food Industry
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series Shipin gongye ke-ji
spelling doaj-art-815b24ca81934fd58499d6501d4fa0fd2025-08-20T02:09:34ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062025-04-0146815616310.13386/j.issn1002-0306.20240404522024040452-8Analysis of Bacterial Communities and Prediction of Functions and Phenotypes in the Preparation of High Temperature Daqu Using Different MethodsHuijun ZHAO0Yurong WANG1Qiangchuan HOU2Haibo ZHANG3Longxin TIAN4Mingbo YE5Zhuang GUO6Brewing Technology Industrial College, Hubei University of Arts and Sciences, Xiangyang 441053, ChinaBrewing Technology Industrial College, Hubei University of Arts and Sciences, Xiangyang 441053, ChinaBrewing Technology Industrial College, Hubei University of Arts and Sciences, Xiangyang 441053, ChinaBrewing Technology Industrial College, Hubei University of Arts and Sciences, Xiangyang 441053, ChinaXiangyang Key Laboratory of Solid State Fermentation of Jiangxiang Baijiu, Xiangyang 441053, ChinaXiangyang Maotai-flavor Baijiu Ecological Brewing Enterprise-University Joint Innovation Center, Xiangyang 441053, ChinaBrewing Technology Industrial College, Hubei University of Arts and Sciences, Xiangyang 441053, ChinaTo compare and analyze the similarities and differences in the bacterial community structure of high temperature Daqu prepared by artificial starter-making and mechanical starter-making, this study used Illumina MiSeq high-throughput sequencing technology to analyze the bacterial community composition of two types of high temperature Daqu samples, and predicted the genetic function and phenotype of the bacteria. Through α-diversity found that there was no significant difference in the diversity and richness of bacteria between artificial and mechanical starter-making samples (P>0.05). The β-diversity showed that there were significant structural differences between the two types of high temperature Daqu samples (P<0.01), and the difference of the bacterial flora of the mechanical starter-making samples was relatively smaller. The analysis of bacterial community structure showed that compared with artificial starter-making samples, the content of Lentibacillus from mechanical starter-making samples was significantly higher (P<0.001), while the content of Weissella, Brevibacterium and Pediococcus was relatively lower (P>0.05). Through LEfSe analysis, it was found that Thermoactinomycetaceae was the biomarker of foot bending, and Bacillaceae was the biomarker of mechanism bending. Through gene function prediction, it was found that compared with artificial starter-making, the signal transduction mechanism of the bacteria in the high-temperature Daqu prepared by mechanical starter-making was significantly higher, and the intracellular transport, secretion and vesicle transport were significantly lower (P<0.05). Through phenotype prediction, it was found that the content of gram-positive bacteria in the mechanical starter-making samples was more abundant (P<0.05), while the ability of oxidative stress tolerance in the artificial starter-making samples was stronger (P<0.05). It could be seen that there were significant differences in the bacterial flora structure between the artificial and mechanical starter-making Daqu, which further affected the function and phenotype of the bacteria. This study can provide basic theory and disciplinary basis for promoting the development of Maotai-flavor Baijiu starter-making samples technology.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024040452artificial starter-makingmechanical starter-makingillumina miseq high-throughput sequencingbacterial floragene functionphenotype
spellingShingle Huijun ZHAO
Yurong WANG
Qiangchuan HOU
Haibo ZHANG
Longxin TIAN
Mingbo YE
Zhuang GUO
Analysis of Bacterial Communities and Prediction of Functions and Phenotypes in the Preparation of High Temperature Daqu Using Different Methods
Shipin gongye ke-ji
artificial starter-making
mechanical starter-making
illumina miseq high-throughput sequencing
bacterial flora
gene function
phenotype
title Analysis of Bacterial Communities and Prediction of Functions and Phenotypes in the Preparation of High Temperature Daqu Using Different Methods
title_full Analysis of Bacterial Communities and Prediction of Functions and Phenotypes in the Preparation of High Temperature Daqu Using Different Methods
title_fullStr Analysis of Bacterial Communities and Prediction of Functions and Phenotypes in the Preparation of High Temperature Daqu Using Different Methods
title_full_unstemmed Analysis of Bacterial Communities and Prediction of Functions and Phenotypes in the Preparation of High Temperature Daqu Using Different Methods
title_short Analysis of Bacterial Communities and Prediction of Functions and Phenotypes in the Preparation of High Temperature Daqu Using Different Methods
title_sort analysis of bacterial communities and prediction of functions and phenotypes in the preparation of high temperature daqu using different methods
topic artificial starter-making
mechanical starter-making
illumina miseq high-throughput sequencing
bacterial flora
gene function
phenotype
url http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024040452
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