Targeting Ferroptosis in Rare Neurological Disorders Including Pediatric Conditions: Innovations and Therapeutic Challenges

Targeting Ferroptosis in Rare Neurological Disorders Including Pediatric Conditions: Innovations and Therapeutic Challenges

Ferroptosis, characterized by iron dependency and lipid peroxidation, has emerged as a key mechanism underlying neurodegeneration in rare neurological disorders. These conditions, often marked by significant therapeutic gaps and high unmet medical needs, present unique challenges for intervention de...

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Main Authors: Ahmed D. Alatawi, Krishnaraju Venkatesan, Khalid Asseri, Premalatha Paulsamy, Saleh F. Alqifari, Rehab Ahmed, Mathar Mohideen Nagoor Thangam, Nizar Sirag, Absar A. Qureshi, Hala Ahmed Elsayes, Zeinab Faried Bahgat, Nesren S. M. Bahnsawy, Kousalya Prabahar, Basma Mahmoud Abd Elhamid Dawood
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biomedicines
Subjects:
ferroptosis
rare neurological disorders
lipid peroxidation
iron metabolism
Online Access:https://www.mdpi.com/2227-9059/13/2/265
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