A two sample Mendelian randomized study of the association of sex hormones and behavioral and clinical risk factors with macular hole

Abstract Macular hole (MH) is a disease of the vitreoretinal interface that develops in relation to age and gender, and is 3.3 times more prevalent in females than in males. However, it remains inconclusive whether gender plays a role in the pathogenesis of MH. We adopted a two-sample Mendelian rand...

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Bibliographic Details
Main Authors: Zetong Nie, Naxin Duan, Xiang Zhang, Boshi Liu, Siqiong Bai, Xiaorong Li, Wenbo Li, Bojie Hu
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-83469-2
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