Intranasal administration of stem cell derivatives for the treatment of AD animal models: a systematic review and meta-analysis

Intranasal administration of stem cell derivatives for the treatment of AD animal models: a systematic review and meta-analysis

Abstract Background Alzheimer’s disease (AD) is a neurodegenerative disorder with increasing prevalence and limited efficacy of current therapies. Stem cell-derived therapies have attracted attention for their potential neurodegenerative and reparative effects. Intranasal administration provides a n...

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Main Authors: Zilin Hua, Nan Zhou, Zijing Zhou, Zewei Fu, Ruiyun Guo, Herman Yao Akogo, Jiayin Yang, Meixuan Yu, Yujie Jiang, Siyi Lan, Haixia Chang, Jun Ma, Huixian Cui
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Stem Cell Research & Therapy
Subjects:
Intranasal administration
Stem cell derivative
Alzheimer’s disease
Systematic review
Meta-analysis
Online Access:https://doi.org/10.1186/s13287-025-04555-4
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https://doi.org/10.1186/s13287-025-04555-4

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