Reduced Muscle Loss in Patients With NSCLC Taking Fibrates: Findings From a Retrospective Observational Study

Reduced Muscle Loss in Patients With NSCLC Taking Fibrates: Findings From a Retrospective Observational Study

ABSTRACT Background The cancer‐anorexia‐cachexia syndrome (CACS) is a common and debilitating wasting disorder characterized by loss of skeletal muscle and worse morbidity and mortality. In pre‐clinical studies, CACS is associated with loss of peroxisome proliferator‐activated receptor alpha (PPAR‐α...

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Main Authors: Rahmi Elahjji, Tahj Blow, Rahul Grover, Maurice A. Hurd, Richard F. Dunne, Bette J. Caan, Elizabeth M. Cespedes Feliciano, Andrew J. Plodkowski, James H. Flory, Marcus D. Goncalves
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
cachexia
fibrates
lung cancer
PPAR‐α
skeletal muscle
Online Access:https://doi.org/10.1002/jcsm.70016
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https://doi.org/10.1002/jcsm.70016

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