Transcriptomic insights into the interplay between polyketide biosynthesis and other secondary metabolite biosynthetic clusters and biological pathways in entomopathogen Beauveria bassiana

Transcriptomic insights into the interplay between polyketide biosynthesis and other secondary metabolite biosynthetic clusters and biological pathways in entomopathogen Beauveria bassiana

Background and aimsThe polyketide synthase gene pks15 plays a critical role in insect virulence and cell wall formation in the entomopathogenic fungus Beauveria bassiana. Metabolomics studies have also shown that this gene exhibits crosstalk with other biosynthetic clusters of beauvericins, bassiano...

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Main Authors: Wachiraporn Toopaang, Thippawan Yoocha, Chaiwat Naktang, Nuchnudda Wichienchote, Phornsiri Pechsrichuang, Sithichoke Tangphatsornruang, Morakot Tanticharoen, Yu-Liang Yang, Alongkorn Amnuaykanjanasin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Microbiology
Subjects:
Beauveria bassiana
polyketide synthase
transcriptome
secondary metabolite
crosstalk
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1583637/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1583637/full

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