Generation of two hiPSC lines carrying compound heterozygous RDH12 mutations in a LCA patient

Leber’s congenital amaurosis (LCA) is a complex inherited retinal dystrophy characterized by severe vision loss and even blindness early in life, caused by more than 38 genes. Variations in RDH12 were found to be responsible for LCA. We successfully generated two induced pluripotent stem cell lines...

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Bibliographic Details
Main Authors: Fuying Guo, Ping Xu, Dandan Zheng, Xiufeng Zhong
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S187350612400223X
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