Enhancing MyD88 oligomerization is one important mechanism by which IBDV VP2 induces inflammatory response.

The inflammatory response is an essential component of innate immunity to defense against pathogens. Infectious bursal disease (IBD) is the most important immunosuppressive disease in chickens and is caused by the infectious bursal disease virus (IBDV). Acute inflammation is a typical pathogenic pro...

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Main Authors: Mengmeng Huang, Mengmeng Xu, Jingzhe Han, Erjing Ke, Xinxin Niu, Yulong Zhang, Guodong Wang, Hangbo Yu, Runhang Liu, Suyan Wang, Yongzhen Liu, Yuntong Chen, Jinze Han, Ziwen Wu, Hongyu Cui, Yanping Zhang, Yulu Duan, Yulong Gao, Xiaole Qi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012985
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