High chromosomal instability is associated with higher 10‐year risks of recurrence for hormone receptor‐positive, human epidermal growth factor receptor 2‐negative breast cancer patients: clinical evidence from a large‐scale, multiple‐site, retrospective study

High chromosomal instability is associated with higher 10‐year risks of recurrence for hormone receptor‐positive, human epidermal growth factor receptor 2‐negative breast cancer patients: clinical evidence from a large‐scale, multiple‐site, retrospective study

Abstract Long‐term survival varies among hormone receptor‐positive (HR+) and human epidermal growth factor receptor 2‐negative (HER2−) breast cancer patients and is seriously impaired by metastasis. Chromosomal instability (CIN) was one of the key drivers of breast cancer metastasis. Here we evaluat...

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Bibliographic Details
Main Authors: Yu‐Yang Liao, Jianfei Fu, Xiang Lu, Ziliang Qian, Yang Yu, Liang Zhu, Jia‐Ni Pan, Pu‐Chun Li, Qiao‐Yan Zhu, Xiaolin Li, Wenyong Sun, Xiao‐Jia Wang, Wen‐Ming Cao
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:The Journal of Pathology: Clinical Research
Subjects:
breast cancer
chromosomal instability
hormone receptor‐positive
recurrence
prognosis
Online Access:https://doi.org/10.1002/2056-4538.70011
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https://doi.org/10.1002/2056-4538.70011

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