Studying the Impact of the DDB2 T338M Missense Mutation on the Development of Equine Squamous Cell Carcinoma and Sarcoid

Studying the Impact of the DDB2 T338M Missense Mutation on the Development of Equine Squamous Cell Carcinoma and Sarcoid

A missense mutation in damage-specific DNA binding protein 2 (DDB2 c.1013 C>T; p.Thr338Met) has been described as a risk factor for ocular squamous cell carcinoma (OSCC) in the Haflinger breed. Here, we examined the impact of DDB2 C>T allele status on the development of OSCC, squamous cell car...

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Bibliographic Details
Main Authors: Hannah Quatember, Barbara Nell, Barbara Richter, Doris Rigler, Marlies Dolezal, Sabine Sykora, Barbara Wallner
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Animals
Subjects:
Haflinger
cancer
eye
tumour
genetic risk factor
DDB2
Online Access:https://www.mdpi.com/2076-2615/15/7/911
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