Intranasal monoclonal antibodies to mugwort pollen reduce allergic inflammation in a mouse model of allergic rhinitis and asthma

Intranasal monoclonal antibodies to mugwort pollen reduce allergic inflammation in a mouse model of allergic rhinitis and asthma

IntroductionAllergen-specific monoclonal antibodies (mAbs) have recently emerged as promising tools in allergy therapy, particularly for patients who do not respond adequately to allergen-specific immunotherapy (AIT). While previous studies have explored systemic delivery routes, the efficacy of loc...

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Main Authors: Kairat Tabynov, Igor Nedushenko, Elmira Tailakova, Akbota Sergazina, Turlan Bolatbekov, Gleb Fomin, Tair Nurpeissov, Utsav Vaghasiya, Nikolai Petrovsky, Anton Demyanov, Yuri Lebedin, Kaissar Tabynov
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
allergen-specific monoclonal antibody
Artemisia vulgaris
intranasal immunotherapy
airway inflammation
allergic rhinitis
asthma
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1595659/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1595659/full

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