PRKCB methylation: a potential biomarker of MDD with childhood chronic stress, a cross-sectional study in drug-naive, first-episode adolescent MDD

PRKCB methylation: a potential biomarker of MDD with childhood chronic stress, a cross-sectional study in drug-naive, first-episode adolescent MDD

The purpose of this study was to investigate the relationship between childhood chronic stress(CCS), Protein kinase C beta (PRKCB) methylation and adolescent major depressive disorder (MDD). After recruiting 100 adolescents with MDD and 50 healthy controls (HCs), we evaluated the severity of CCS. PR...

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Main Authors: Yuanmei Tao, Meijiang Jin, Hang Zhang, Maojia Ran, Hanmei Xu, Shoukang Zou, Fang Deng, Lijuan Huang, Hong Zhang, Xiaolan Wang, Yanping Wang, Huijin Hou, Shufang Liang, Xiaohong Ma, Li Yin
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Epigenetics
Subjects:
Adolescent MDD
childhood chronic stress
PRKCB
DNA methylation
Online Access:https://www.tandfonline.com/doi/10.1080/15592294.2024.2408159
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https://www.tandfonline.com/doi/10.1080/15592294.2024.2408159

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