Induction of Cell Death by Combined Treatment with Photosensitizer‐Chitosan Nanoparticles and the Ferroptosis Inducer RSL3 in Breast Cancer Cell Lines

Induction of Cell Death by Combined Treatment with Photosensitizer‐Chitosan Nanoparticles and the Ferroptosis Inducer RSL3 in Breast Cancer Cell Lines

Breast cancer, a prevalent malignancy worldwide, includes the triple‐negative subtype (TNBC) characterized by poor treatment outcomes. TNBC has been shown to be sensitive to ferroptotic cell death, an iron‐dependent cell death mechanism involving reactive oxygen species (ROS) and lipid peroxidation....

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Main Authors: Marek Feith, Saikat Das Sajib, Anne Grethe Myrann, Anders Høgset, Pablo Garrido, Alfredo Martinez, Erik Knutsen, Kirsten Sandvig, Tore Skotland, Gunhild Mari Mælandsmo, Tore‐Geir Iversen
Format: Article
Language:English
Published: Wiley-VCH 2025-05-01
Series:Advanced NanoBiomed Research
Subjects:
cell metabolism
glutathione peroxidase 4
lipid peroxidation
triple‐negative breast cancer
Online Access:https://doi.org/10.1002/anbr.202400208
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https://doi.org/10.1002/anbr.202400208

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