RNA-binding proteins in ALS and FTD: from pathogenic mechanisms to therapeutic insights
Abstract Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are devastating neurodegenerative disorders with overlapping clinical, genetic and pathological features. A large body of evidence highlights the critical role of RNA-binding proteins (RBPs) – in particular TAR DNA-bindin...
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| Main Authors: | Jens Rummens, Sandrine Da Cruz |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
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| Series: | Molecular Neurodegeneration |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13024-025-00851-y |
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