RNA-binding proteins in ALS and FTD: from pathogenic mechanisms to therapeutic insights

Abstract Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are devastating neurodegenerative disorders with overlapping clinical, genetic and pathological features. A large body of evidence highlights the critical role of RNA-binding proteins (RBPs) – in particular TAR DNA-bindin...

Full description

Saved in:
Bibliographic Details
Main Authors: Jens Rummens, Sandrine Da Cruz
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s13024-025-00851-y
Tags: Add Tag
No Tags, Be the first to tag this record!