Interleukin-15 and cancer: some solved and many unsolved questions

Interleukin-15 and cancer: some solved and many unsolved questions

Soluble interleukin (IL)-15 exists under two forms: as monomer (sIL-15) or as heterodimeric complex in association with sIL-15Rα (sIL-15/IL-15Rα). Both forms have been successfully tested in experimental tumor murine models and are currently undergoing investigation in phase I/II clinical trials. De...

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Bibliographic Details
Main Authors: Gabriella Pietra, Lorenzo Moretta, Nicola Tumino, Piera Filomena Fiore, Sabina Di Matteo, Francesca Romana Mariotti, Selene Ottonello, Simone Negrini, Barbara Bottazzi, Erwan Mortier, Bruno Azzarone
Format: Article
Language:English
Published: BMJ Publishing Group 2020-10-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e001428.full
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https://jitc.bmj.com/content/8/2/e001428.full

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