Efficacy of Cevimeline on Xerostomia in Sjögren's Syndrome Patients: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Efficacy of Cevimeline on Xerostomia in Sjögren's Syndrome Patients: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Background: Xerostomia, or dry mouth, is a common and debilitating symptom in patients with Sjögren's syndrome, affecting their quality of life. Although Cevimeline, a muscarinic agonist, has been investigated as a potential treatment, its efficacy and optimal dosage remain uncertain. This stud...

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Main Authors: Mehdi Karimi, MD, Fatemeh Ahmadi Hajikolaei, MD, Fahime Hoseinpour, MD, Seyed-Ali Hashemi, MD, Anita Fatehi, MD, Seyed-Abbas Pakmehr, MD, Niloofar Deravi, MD, Mahdyieh Naziri, MSc, Mohaddeseh Belbasi, MD, Sahar Khoshravesh, MD, Seyed Hossein Vaezzadeh, MD
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Therapeutic Research
Subjects:
autoimmune
cevimeline
dry mouth
meta-analysis
Sjogren syndrome
xerostomia
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X24000407
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