High Hcy regulates fluid shear stress pathway activity through histone H3K79 homocysteinylation in hyperhomocysteinemia-related child hypertension

Abstract Background The rise of hypertension in children has been increasingly associated with hyperhomocysteinemia (HHcy), which is recognized as a major risk factor. However, the underlying mechanisms linking homocysteine and hypertension (termed HHYP) are not fully understood. Methods This study...

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Bibliographic Details
Main Authors: Baoling Bai, Lingyun Liu, Yanyan Liu, Shuangshuang Yang, Haojie Wu, Kexin Zhang, Lin Shi, Qin Zhang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Translational Medicine
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Online Access:https://doi.org/10.1186/s12967-025-06483-6
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