Metabolomics of the interaction between PPAR‐α and age in the PPAR‐α‐null mouse

Metabolomics of the interaction between PPAR‐α and age in the PPAR‐α‐null mouse

Abstract Regulation between the fed and fasted states in mammals is partially controlled by peroxisome proliferator‐activated receptor‐α (PPAR‐α). Expression of the receptor is high in the liver, heart and skeletal muscle, but decreases with age. A combined 1H nuclear magnetic resonance (NMR) spectr...

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Main Authors: Helen J Atherton, Melanie K Gulston, Nigel J Bailey, Kian‐Kai Cheng, Wen Zhang, Kieran Clarke, Julian L Griffin
Format: Article
Language:English
Published: Springer Nature 2009-04-01
Series:Molecular Systems Biology
Subjects:
functional genomics
hepatic steatosis
metabonomics
obesity
Online Access:https://doi.org/10.1038/msb.2009.18
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https://doi.org/10.1038/msb.2009.18

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