Persistent accumulation of therapy-induced senescent cells: an obstacle to long-term cancer treatment efficacy

Abstract In the ever-evolving landscape of cancer therapy, while cancer treatments such as chemotherapy, radiotherapy, and targeted therapy aim to eradicate malignant cells, they also inadvertently trigger cellular senescence in both cancerous and microenvironmental tissues. Therapy-induced senescen...

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Bibliographic Details
Main Authors: Jingjing Luo, Tongxu Sun, Zhenghui Liu, Yangfan Liu, Junjiang Liu, Shimeng Wang, Xueke Shi, Hongmei Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-025-00380-w
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