A novel lncRNA YIL163C enhances genomic stability and antifungal resistance via the DNA damage response in Saccharomyces cerevisiae

A novel lncRNA YIL163C enhances genomic stability and antifungal resistance via the DNA damage response in Saccharomyces cerevisiae

IntroductionLong non-coding RNAs (lncRNAs) are increasingly recognized as key regulators in cellular processes, including the DNA damage response (DDR). In Saccharomyces cerevisiae, DDR is critical for maintaining genomic integrity under stress, mediated by proteins like Mec1 and Rad53. However, the...

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Bibliographic Details
Main Authors: Xueting Wang, Xuemei Li, Duoyun Li, Yiying Zhang, Bing Bai, Bao Chai, Zewen Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Microbiology
Subjects:
lncRNA
DNA damage response
5-fluorocytosine
phosphoproteome
YIL163C
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1571797/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1571797/full

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