Deep MALDI-MS spatial omics guided by quantum cascade laser mid-infrared imaging microscopy

Deep MALDI-MS spatial omics guided by quantum cascade laser mid-infrared imaging microscopy

Abstract In spatial’omics, highly confident molecular identifications are indispensable for the investigation of complex biology and for spatial biomarker discovery. However, current mass spectrometry imaging (MSI)-based spatial ‘omics must compromise between data acquisition speed and biochemical p...

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Main Authors: Lars Gruber, Stefan Schmidt, Thomas Enzlein, Huong Giang Vo, Tobias Bausbacher, James Lucas Cairns, Yasemin Ucal, Florian Keller, Martina Kerndl, Denis Abu Sammour, Omar Sharif, Gernot Schabbauer, Rüdiger Rudolf, Matthias Eckhardt, Stefania Alexandra Iakab, Laura Bindila, Carsten Hopf
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59839-3
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https://doi.org/10.1038/s41467-025-59839-3

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