Hypoxia-inducible factor-1 alpha and nuclear factor erythroid 2-related factor 2 as biomarkers of renal scarring in children with congenital anomalies of the kidney and urinary tract: a prospective case-control study

Abstract Background Congenital anomalies of the kidney and urinary tract (CAKUT) represent a diverse group of structural malformations that can lead to renal fibrosis and chronic kidney disease in children. Although hypoxia-inducible factor-1 alpha (HIF-1α) and nuclear factor erythroid 2-related fac...

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Bibliographic Details
Main Authors: Aylin Gençler, Hakim Çelik, Fatih Padalı, Abit Demir, Safiye Kafadar
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Nephrology
Subjects:
Online Access:https://doi.org/10.1186/s12882-025-04193-1
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