Onset of End-Stage Atrophic Age-Related Macular Degeneration as an End Point—A Delphi Study: Classification of Atrophy Meetings Report 7

Onset of End-Stage Atrophic Age-Related Macular Degeneration as an End Point—A Delphi Study: Classification of Atrophy Meetings Report 7

Purpose: To investigate whether consensus can be reached on the acceptability of end-stage atrophy onset as a clinical end point in early intervention trials of age-related macular degeneration (AMD), and the criteria for defining such an end point. Design: A modified Delphi study. Participants: Int...

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Main Authors: Zhichao Wu, BAppSc(Optom), PhD, Srinivas R. Sadda, MD, Thomas Ach, MD, Barbara A. Blodi, MD, Ferdinando Bottoni, MD, Usha Chakravarthy, MD, PhD, Emily Y. Chew, MD, Christine A. Curcio, PhD, Frederick L. Ferris, III, MD, Monika Fleckenstein, MD, K. Bailey Freund, MD, Juan E. Grunwald, MD, Frank G. Holz, MD, Glenn J. Jaffe, MD, Sandra Liakopoulos, MD, Tock Han Lim, FRCSEd, Jordi M. Monés, MD, PhD, Sergio Pagliarini, MD, FRCOphth, Daniel Pauleikhoff, MD, Maximilian Pfau, MD, Philip J. Rosenfeld, MD, PhD, David Sarraf, MD, Steffen Schmitz-Valckenberg, MD, Richard F. Spaide, MD, Janet R. Sparrow, PhD, Giovanni Staurenghi, MD, Adnan Tufail, MD, Francesco Viola, MD, Robyn H. Guymer, MBBS, PhD
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Ophthalmology Science
Subjects:
Age-related macular degeneration
Geographic atrophy
Drusen
Delphi
Microperimetry
Online Access:http://www.sciencedirect.com/science/article/pii/S2666914525000752
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