Impact of co-infections and BCG immunisation on immune responses among household contacts of tuberculosis patients in a Ugandan cohort.

Impact of co-infections and BCG immunisation on immune responses among household contacts of tuberculosis patients in a Ugandan cohort.

<h4>Background</h4>Tuberculosis incidence in resource poor countries remains high. We hypothesized that immune modulating co-infections such as helminths, malaria, and HIV increase susceptibility to latent tuberculosis infection (LTBI), thereby contributing to maintaining the tuberculosi...

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Main Authors: Irene A Biraro, Moses Egesa, Frederic Toulza, Jonathan Levin, Stephen Cose, Moses Joloba, Steven Smith, Hazel M Dockrell, Achilles Katamba, Alison M Elliott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0111517
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https://doi.org/10.1371/journal.pone.0111517

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