Distinct antibody responses of patients with mild and severe leptospirosis determined by whole proteome microarray analysis.

Distinct antibody responses of patients with mild and severe leptospirosis determined by whole proteome microarray analysis.

<h4>Background</h4>Leptospirosis is an important zoonotic disease worldwide. Humans usually present a mild non-specific febrile illness, but a proportion of them develop more severe outcomes, such as multi-organ failure, lung hemorrhage and death. Such complications are thought to depend...

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Main Authors: Carolina Lessa-Aquino, Janet C Lindow, Arlo Randall, Elsio Wunder, Jozelyn Pablo, Rie Nakajima, Algis Jasinskas, Jaqueline S Cruz, Alcineia O Damião, Nívison Nery, Guilherme S Ribeiro, Federico Costa, José E Hagan, Mitermayer Galvão Reis, Albert I Ko, Marco Alberto Medeiros, Philip L Felgner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0005349&type=printable
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https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0005349&type=printable

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