FBL promotes hepatocellular carcinoma tumorigenesis and progression by recruiting YY1 to enhance CAD gene expression

Abstract Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Accumulating evidence suggests that epigenetic dysregulation contributes to the initiation and progression of HCC. We aimed to investigate key epigenetic regulators that contribute to tumorigenesis...

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Main Authors: Yafei Zhi, Yan Guo, Shiliang Li, Xinyu He, Huifang Wei, Kyle Laster, Qiong Wu, Dengyun Zhao, Jinxin Xie, Shanshan Ruan, Nicholas R. Lemoine, Honglin Li, Zigang Dong, Kangdong Liu
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07684-z
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