Phase 2 Trial of Stereotactic Body Radiation Therapy with Dose Escalation Using Simultaneous Integrated Boost for Spinal Metastases

Phase 2 Trial of Stereotactic Body Radiation Therapy with Dose Escalation Using Simultaneous Integrated Boost for Spinal Metastases

Purpose: Stereotactic body radiation therapy (SBRT) is an effective treatment approach for spinal metastases. However, local recurrence may occur. This prospective phase 2 trial evaluated whether SBRT with dose escalation in the gross tumor volume through simultaneous integrated boost (SIB–SBRT) can...

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Main Authors: Takamasa Mitsuyoshi, MD, PhD, Peter J. K. Tokuda, MD, Yumi Kokubo, MD, Takahiro Iwai, MD, Hiroyuki Inoo, MD, Ryo Ashida, MD, PhD, Ryosuke Nasada, MS, Mikiko Yamashita, PhD, Hiroaki Tanabe, MS, Shigeki Arizono, MD, PhD, Toshiyuki Imagumbai, MD, Masaki Kokubo, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S245210942500048X
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