The Spatial Proximity of CD8<sup>+</sup> FoxP3<sup>+</sup>PD-1<sup>+</sup> Cells to Tumor Cells: A More Accurate Predictor of Immunotherapy Outcomes in Advanced Non-Small-Cell Lung Cancer

The Spatial Proximity of CD8<sup>+</sup> FoxP3<sup>+</sup>PD-1<sup>+</sup> Cells to Tumor Cells: A More Accurate Predictor of Immunotherapy Outcomes in Advanced Non-Small-Cell Lung Cancer

Background: To optimize precision immunotherapy for advanced NSCLC, comprehensive tumor immune microenvironment (TIME) characterization is crucial for efficacy prediction. Methods: Pretreatment tumor samples from 46 advanced NSCLC patients treated with PD-1/PD-L1 inhibitors were analyzed. The subreg...

Full description

Saved in:
Bibliographic Details
Main Authors: Zijuan Hu, Zhihuang Hu, Keji Chen, Huixia Huang, Xinyang Zhong, Yaxian Wang, Jiayu Chen, Xuefeng He, Di Shi, Yupeng Zeng, Jiwei Li, Xiaoyan Zhou, Ping Wei
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Current Oncology
Subjects:
CD8<sup>+</sup>FoxP3<sup>+</sup>PD-1<sup>+</sup> cells
spatial proximity
PD-1/PD-L1 blockade
therapeutic outcomes
advanced non-small-cell lung cancer
Online Access:https://www.mdpi.com/1718-7729/32/5/262
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1718-7729/32/5/262

Similar Items