Double Deletion of EP402R and EP153R in the Attenuated Lv17/WB/Rie1 African Swine Fever Virus (ASFV) Enhances Safety, Provides DIVA Compatibility, and Confers Complete Protection Against a Genotype II Virulent Strain

Double Deletion of EP402R and EP153R in the Attenuated Lv17/WB/Rie1 African Swine Fever Virus (ASFV) Enhances Safety, Provides DIVA Compatibility, and Confers Complete Protection Against a Genotype II Virulent Strain

<b>Background/Objectives:</b> African swine fever virus (ASFV) is a devastating disease affecting domestic and wild suids and causing significant economic losses in the global pig industry. Attenuated modified live virus (MLV) vaccines are the most promising approaches for vaccine develo...

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Main Authors: Carmina Gallardo, István Mészáros, Alejandro Soler, Jovita Fernandez-Pinero, Erwin van den Born, Alicia Simón, Nadia Casado, Raquel Nieto, Covadonga Perez, Irene Aldea, Vicente Lopez-Chavarrias, Eszter Göltl, Ferenc Olasz, Tibor Magyar, Zoltán Zádori, José Manuel Sánchez-Vizcaíno, Marisa Arias
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Vaccines
Subjects:
ASFV
attenuated virus
Lv17/WB/Rie1
vaccine
EP402R
EP153R
Online Access:https://www.mdpi.com/2076-393X/12/12/1406
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