Genistein Reduces Anxiety-like Behavior During Metestrus–Diestrus Phase Without Changing Estradiol or Progesterone Levels in Wistar Rats

Genistein Reduces Anxiety-like Behavior During Metestrus–Diestrus Phase Without Changing Estradiol or Progesterone Levels in Wistar Rats

<b>Background</b>: Premenstrual syndrome is characterized by emotional changes, including anxiety and depression symptoms, which may be treated with anxiolytic and antidepressant drugs, as well as estrogen therapy. However, steroidal estrogen therapy is contraindicated for patients with...

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Main Authors: Juan Francisco Rodríguez-Landa, Oscar Jerónimo Olmos-Vázquez, Carlos Fabrizio Quiñonez-Bailón, Gabriel Guillén-Ruiz, Ana Karen Limón-Vázquez, Jonathan Cueto-Escobedo, Eduardo Rivadeneyra-Domínguez, Blandina Bernal-Morales
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Metabolites
Subjects:
anxiety
premenstrual syndrome
phytoestrogens
alternative therapy
ovarian cycle
rat
Online Access:https://www.mdpi.com/2218-1989/15/5/311
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