Gender-affirming hormonal therapy induces a gender-concordant fecal metagenome transition in transgender individuals

Gender-affirming hormonal therapy induces a gender-concordant fecal metagenome transition in transgender individuals

Abstract Background Limited data exists regarding gender-specific microbial alterations during gender-affirming hormonal therapy (GAHT) in transgender individuals. This study aimed to investigate the nuanced impact of sex steroids on gut microbiota taxonomy and function, addressing this gap. We pros...

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Main Authors: Timur Liwinski, Matthias K. Auer, Johanna Schröder, Ina Pieknik, Christian Casar, Dorothee Schwinge, Lara Henze, Günter K. Stalla, Undine E. Lang, Alina von Klitzing, Peer Briken, Thomas Hildebrandt, Jeanne C. Desbuleux, Sarah V. Biedermann, Paul-Martin Holterhus, Corinna Bang, Christoph Schramm, Johannes Fuss
Format: Article
Language:English
Published: BMC 2024-09-01
Series:BMC Medicine
Subjects:
Gender-affirming hormonal therapy
Sex steroids
Microbiome
Microbiota
Metagenome
Trans women
Online Access:https://doi.org/10.1186/s12916-024-03548-z
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https://doi.org/10.1186/s12916-024-03548-z

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