Early diagnosis of progressive multifocal leukoencephalopathy in untreated HIV infection via ultrasensitive PCR testing for JC virus: A case report

Early diagnosis of progressive multifocal leukoencephalopathy in untreated HIV infection via ultrasensitive PCR testing for JC virus: A case report

Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease triggered by the reactivation of JC virus (JCV) in individuals with immunodeficiency, particularly those with untreated human immunodeficiency virus (HIV) infection. This case report describes a 46-year-old HIV-positiv...

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Main Authors: Kenji Nakano, Akira Kawashima, Takato Nakamoto, Kazuo Nakamichi, Ryo Kuwata, Seitaro Abe, Eri Inoue, Naokatsu Ando, Haruka Uemura, Daisuke Mizushima, Takahiro Aoki, Katsuji Teruya, Hiroyuki Gatanaga
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:IDCases
Subjects:
Human immunodeficiency virus
Progressive multifocal leukoencephalopathy
Ultrasensitive polymerase chain reaction
Online Access:http://www.sciencedirect.com/science/article/pii/S2214250925000848
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