Unraveling the genetic connections for mitochondrial DNA control region and breast cancer susceptibility

Unraveling the genetic connections for mitochondrial DNA control region and breast cancer susceptibility

Abstract Breast cancer, a complex global health concern, has predominantly been studied for nuclear DNA variations. However, the role of mitochondrial DNA (mtDNA) haplogroups in breast cancer susceptibility, especially in Pakistan, remains underexplored. This case-control study investigates the asso...

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Bibliographic Details
Main Authors: Namra Khalid, Muhammad Umer Khan, Raima Rehman, Shamsa Kanwal, Tazeen Zahid, Muhammad Usman Ghani, Ayesha Iftikhar, Qurban Ali, Muhammad Arshad Javed
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Breast cancer
Mitochondrial DNA
Variants
Haplogroups
Sequencing
Online Access:https://doi.org/10.1038/s41598-025-89115-9
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