Genetic map of the carotid body stem cell niche with focus on the O2-sensing chemoreceptor cell lineage

Abstract Adaptive homeostatic responses to oxygen (O2) deficiency (hypoxia) are essential for survival. The prototypical acute O2-sensing organ is the carotid body (CB), a neural crest-derived tissue with chemoreceptor glomus cells that express hypoxia-inhibited K+ channels. This, in turn, leads to...

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Bibliographic Details
Main Authors: Ana Santamaría-Santiago, Verónica Sobrino, Luis Luna-Ramírez, José López-Barneo, Ricardo Pardal
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-12397-6
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