TP53 mutational status is a potential marker for risk stratification in Wilms tumour with diffuse anaplasia.

TP53 mutational status is a potential marker for risk stratification in Wilms tumour with diffuse anaplasia.

<h4>Purpose</h4>The presence of diffuse anaplasia in Wilms tumours (DAWT) is associated with TP53 mutations and poor outcome. As patients receive intensified treatment, we sought to identify whether TP53 mutational status confers additional prognostic information.<h4>Patients and m...

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Main Authors: Mariana Maschietto, Richard D Williams, Tasnim Chagtai, Sergey D Popov, Neil J Sebire, Gordan Vujanic, Elizabeth Perlman, James R Anderson, Paul Grundy, Jeffrey S Dome, Kathy Pritchard-Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0109924
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https://doi.org/10.1371/journal.pone.0109924

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