Mesenchymal Stem Cells Alleviate Renal Fibrosis and Inhibit Autophagy via Exosome Transfer of miRNA-122a

Exosomes derived from mesenchymal stem cell (MSC) alleviate kidney damage through autophagy. This study determined whether MSCs relieve renal fibrosis and inhibit autophagy by exosome transfer of miRNA-122a. The gene expression involved in the mTOR signaling pathway and autophagy was assessed in TGF...

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Bibliographic Details
Main Authors: Dawei Li, Junwen Qu, Xiaodong Yuan, Shaoyong Zhuang, Haoyu Wu, Ruoyang Chen, Jiajin Wu, Ming Zhang, Liang Ying
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2022/1981798
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