PCL scaffold with well-defined hierarchical pores effectively controls cell migration and alignment of human mesenchymal stem cells

Abstract With an increasing incidence of orthopedic fractures due to the growing aging population, the demand for novel bone tissue engineering treatments is rising. Existing biopolymeric scaffolds have hierarchical structure, are biocompatible, and are biodegradable, but struggle to control pore si...

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Bibliographic Details
Main Authors: Se-Hwan Lee, Jaeyeon Lee, Nae-Un Kang, Yong Sang Cho, Su Chin Heo, Yongdoo Park, Young-Sam Cho
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-96027-1
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