Mechanism of the blood-brain barrier modulation by cadherin peptides
Aim: This study was aimed at finding the binding site on the human E-cadherin for Ala-Asp-Thr Cyclic 5 (ADTC5), ADTC7, and ADTC9 peptides as blood-brain barrier modulator (BBBM) for determining their mechanism of action in modulating the blood-brain barrier (BBB). Methods: ADTC7 and ADTC9 were deriv...
Saved in:
Main Authors: | Elinaz Farokhi, Ahmed L. Alaofi, Vivitri D. Prasasty, Filia Stephanie, Marlyn D. Laksitorini, Krzysztof Kuczera, Teruna J. Siahaan |
---|---|
Format: | Article |
Language: | English |
Published: |
Open Exploration
2024-06-01
|
Series: | Exploration of Drug Science |
Subjects: | |
Online Access: | https://www.explorationpub.com/uploads/Article/A100849/100849.pdf |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Role of E-cadherin in epithelial barrier dysfunction: implications for bacterial infection, inflammation, and disease pathogenesis
by: Peter Lialios, et al.
Published: (2025-02-01) -
Triiodothyronine treatment in mice improves stroke outcome and reduces blood–brain barrier damage
by: Daniel Ullrich, et al.
Published: (2025-02-01) -
MicroRNA-155 modulates methotrexate-induced spatial memory impairment by disruption of the blood-brain barrier integrity
by: Yu-Chieh Chen, et al.
Published: (2025-03-01) -
A comprehensive insight of innovations and recent advancements in nanocarriers for nose-to-brain drug targeting
by: Naeem Mubarak, et al.
Published: (2025-12-01) -
α-catenin phosphorylation is elevated during mitosis to resist apical rounding and epithelial barrier leak
by: Phuong M. Le, et al.
Published: (2025-01-01)