Crossing the barrier or how regulation of ovastacin controls fertilization and translates into clinical phenotypes
Summary: The zona pellucida, a glycoprotein matrix enveloping the mammalian egg, exerts essential functions during fertilization and early embryonic development. Its safeguard property regulates sperm entry and thus indirectly controls fertility. Limited proteolysis by the metalloproteinase ovastaci...
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| Main Authors: | Nele von Wiegen, Christian Behl, Hagen Körschgen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
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| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004225012374 |
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