WNT4 promotes the symmetric fission of crypt in radiation-induced intestinal epithelial regeneration

Abstract Background Radiotherapy for pelvic malignant tumors inevitably causes intestinal tissue damage. The regeneration of intestinal epithelium after radiation injury relies mainly on crypt fission. However, little is known about the regulatory mechanisms of crypt fission events. Methods The effe...

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Bibliographic Details
Main Authors: Jingyang Cheng, Haiyong Wu, Yanmei Cui
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:https://doi.org/10.1186/s11658-024-00677-4
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