Investigating the protective effects of fluvoxamine against sepsis-related acute lung injury through antiapoptotic, anti-inflammatory, and anti-oxidant features in rats

Investigating the protective effects of fluvoxamine against sepsis-related acute lung injury through antiapoptotic, anti-inflammatory, and anti-oxidant features in rats

Objective(s): Acute lung injury (ALI) is characterized by severe hypoxia and alveolar damage, often caused by oxidative stress, endoplasmic reticulum stress (ERS), and apoptosis. Fluvoxamine (FLV), an antidepressant, has tissue-protective properties through various intracellular mechanisms. This stu...

Full description

Saved in:
Bibliographic Details
Main Authors: Halil Asci, Suleyman Emre Akin, Hasan Ekrem Camas, Ahmet Bindal, Okan Kurtbolat, Şerife Tasan, Abdurrahman Gulal, Rumeysa Taner, Turgut Kurt, Ozlem Ozmen
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-03-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
er stress
inflammation
lipopolysaccharide
rat
respiratory system
ssri
Online Access:https://ijbms.mums.ac.ir/article_25368_f8d5d1d20907e7f3a91fe1f4c610e020.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://ijbms.mums.ac.ir/article_25368_f8d5d1d20907e7f3a91fe1f4c610e020.pdf

Similar Items