Human hepatoma Huh-7 cell culture models deficient in apolipoprotein B secretion

Human hepatoma Huh-7 cell culture models deficient in apolipoprotein B secretion

ApoB is an essential structural protein for the assembly and secretion of triglyceride-rich lipoproteins and therefore remains a potential target to lower plasma cholesterol levels in hypercholesterolemia patients. To understand the global consequences of APOB gene deficiency, we employed CRISPR-Cas...

Full description

Saved in:
Bibliographic Details
Main Authors: Swati Valmiki, Sara Rosario, Ashley Mooring, Chandana Prakashmurthy, Florencia Schlamp, Binu Prakash, Atrayee Chattopadhyay, Abulaish Ansari, José O. Alemán, Nathalie Pamir, M. Mahmood Hussain
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Lipid Research
Subjects:
apoB100
lipid transport
CRISPR-Cas9
DNA replication
coagulation
vitamin D binding protein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227525001294
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S0022227525001294

Similar Items