In Silico and In Vitro Studies to Explore the Effect of Thymoquinone on Isocitrate Lyase, Biofilm Formation, and the Expression of Some Virulence Genes in <i>Candida albicans</i>

In Silico and In Vitro Studies to Explore the Effect of Thymoquinone on Isocitrate Lyase, Biofilm Formation, and the Expression of Some Virulence Genes in <i>Candida albicans</i>

Thymoquinone (TQ), a bioactive compound from black cumin (<i>Nigella sativa</i>), has demonstrated a broad range of therapeutic effects. The aim of this study is to evaluate the antifungal efficacy of TQ by targeting key virulence factors in <i>Candida albicans</i>, specifica...

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Bibliographic Details
Main Authors: Masood Alam Khan, Mohd Azam, Hina Younus
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Current Issues in Molecular Biology
Subjects:
black cumin
thymoquinone
virulence genes
infection
<i>Candida albicans</i>
molecular dynamics
Online Access:https://www.mdpi.com/1467-3045/46/11/771
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