Placental transfer of SARS-CoV-2 antibodies in mother-neonate pairs: a prospective nested cohort study

Placental transfer of SARS-CoV-2 antibodies in mother-neonate pairs: a prospective nested cohort study

Abstract Background Newborns depend on the transfer of IgG across the placenta to acquire protection against pathogens. We assessed the placental transfer of SARS-CoV-2 antibodies, primarily derived from infection, from seropositive pregnant women enrolled in a pregnancy cohort in Kilifi, Kenya. Met...

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Main Authors: Alex G. Mugo, Angela Koech, Liberty Cantrell, Moses Mukhanya, Isaac Mwaniki, Joseph Mutunga, Merryn Voysey, Rachel Craik, Peter von Dadelszen, Kirsty Le Doare, Marleen Temmerman, Geoffrey Omuse, periCOVID-Africa, The PRECISE Network
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Infectious Diseases
Subjects:
COVID-19
SARS-CoV-2 antibodies
Seropositivity
Placental transfer
Efficiency
Online Access:https://doi.org/10.1186/s12879-025-11225-6
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https://doi.org/10.1186/s12879-025-11225-6

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