Federated target trial emulation using distributed observational data for treatment effect estimation

Abstract Target trial emulation (TTE) aims to estimate treatment effects by simulating randomized controlled trials using real-world observational data. Applying TTE across distributed datasets shows great promise in improving generalizability and power but is always infeasible due to privacy and da...

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Bibliographic Details
Main Authors: Haoyang Li, Chengxi Zang, Zhenxing Xu, Weishen Pan, Suraj Rajendran, Yong Chen, Fei Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-025-01803-y
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